Rujun Gong Selected Research

Glycogen Synthase Kinases

1/2021	Rationale and Design of Assessing the Effectiveness of Short-Term Low-Dose Lithium Therapy in Averting Cardiac Surgery-Associated Acute Kidney Injury: A Randomized, Double Blinded, Placebo Controlled Pilot Trial.
1/2020	Relapse of Nephrotic Syndrome after Adrenocorticotropic Hormone-Induced Remission: Implications of Adrenocorticotropic Hormone Antibodies.
1/2020	Glycogen synthase kinase 3β hyperactivity in urinary exfoliated cells predicts progression of diabetic kidney disease.
1/2018	Activation of mineralocorticoid receptor by ecdysone, an adaptogenic and anabolic ecdysteroid, promotes glomerular injury and proteinuria involving overactive GSK3β pathway signaling.
11/2016	Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease via targeting GSK3β.
5/2016	The β isoform of GSK3 mediates podocyte autonomous injury in proteinuric glomerulopathy.
11/2015	Remote ischemic preconditioning for kidney protection: GSK3β-centric insights into the mechanism of action.
2/2015	Pharmacological targeting of GSK3β confers protection against podocytopathy and proteinuria by desensitizing mitochondrial permeability transition.
12/2013	Redox-sensitive glycogen synthase kinase 3β-directed control of mitochondrial permeability transition: rheostatic regulation of acute kidney injury.
4/2012	Inhibition of glycogen synthase kinase-3β prevents NSAID-induced acute kidney injury.

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Rujun Gong Research Topics

Disease

18	Proteinuria 01/2022 - 11/2004
17	Fibrosis (Cirrhosis) 01/2021 - 12/2003
13	Inflammation (Inflammations) 10/2020 - 11/2004
12	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 01/2011
11	Chronic Renal Insufficiency 01/2019 - 12/2003
6	Albuminuria 11/2021 - 11/2015
6	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2020 - 12/2011
5	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2022 - 03/2014
4	Kidney Diseases (Kidney Disease) 01/2021 - 03/2008
4	Diabetic Nephropathies (Diabetic Nephropathy) 01/2020 - 01/2019
4	Necrosis 10/2018 - 04/2012
4	Ischemia 11/2016 - 07/2013
4	Neoplasms (Cancer) 01/2016 - 10/2013
3	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 01/2022 - 03/2014
3	Body Weight (Weight, Body) 01/2021 - 03/2013
3	Atrophy 01/2021 - 11/2016
3	Sclerosis 01/2019 - 01/2012
3	Hepatocellular Carcinoma (Hepatoma) 07/2014 - 04/2013
3	Ureteral Obstruction 05/2012 - 08/2010
2	Infections 01/2021 - 01/2015
2	Mood Disorders (Mood Disorder) 01/2021 - 12/2016
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2020 - 04/2005
2	Wounds and Injuries (Trauma) 01/2019 - 02/2015
2	Nephritis 01/2016 - 03/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 05/2015 - 02/2015
2	Vascular System Injuries 01/2012 - 01/2005
2	Lupus Nephritis 05/2007 - 02/2002
1	Nephrosis 01/2022
1	Hyperglycemia 01/2021
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021
1	Acne Vulgaris 10/2020
1	Experimental Melanoma 01/2020
1	Diabetes Complications 01/2019
1	Hyperplasia 01/2019
1	Barotrauma 01/2019

Drug/Important Bio-Agent (IBA)

10	Glycogen Synthase KinasesIBA 01/2021 - 04/2012
9	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2022 - 12/2011
9	Peptides (Polypeptides)IBA 01/2022 - 01/2005
9	LithiumIBA 01/2021 - 03/2014
7	MelanocortinsIBA 01/2022 - 03/2014
6	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 10/2014
6	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 03/2008 - 12/2003
5	SteroidsIBA 01/2022 - 12/2011
5	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021 - 08/2014
5	CytokinesIBA 01/2020 - 03/2008
4	Melanocortin Receptors (Melanocortin Receptor)IBA 01/2021 - 01/2016
4	AntioxidantsIBA 01/2019 - 11/2008
4	AldosteroneIBA 05/2015 - 09/2011
4	CollagenIBA 01/2015 - 12/2003
4	SurvivinIBA 07/2014 - 04/2013
3	Hormones (Hormone)IBA 01/2021 - 03/2014
3	Cisplatin (Platino)FDA LinkGeneric 12/2019 - 03/2014
3	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2019 - 05/2015
3	4- benzyl- 2- methyl- 1,2,4- thiadiazolidine- 3,5- dioneIBA 06/2015 - 04/2012
3	ErbB Receptors (EGF Receptor)IBA 07/2013 - 01/2012
3	NF-kappa B (NF-kB)IBA 01/2012 - 11/2004
2	Streptozocin (Streptozotocin)FDA Link 11/2021 - 01/2021
2	AntigensIBA 01/2020 - 03/2012
2	AntibodiesIBA 01/2020 - 07/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2018 - 03/2010
2	Immunosuppressive Agents (Immunosuppressants)IBA 07/2017 - 12/2011
2	Neutralizing AntibodiesIBA 07/2017 - 12/2003
2	tanshinoneIBA 11/2016 - 01/2015
2	Fibronectins (Fibronectin)IBA 11/2016 - 01/2015
2	Phosphotransferases (Kinase)IBA 11/2015 - 01/2012
2	Growth Factor ReceptorsIBA 05/2015 - 01/2012
2	Extracellular Matrix ProteinsIBA 07/2013 - 08/2010
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2012 - 12/2010
2	ChemokinesIBA 12/2010 - 11/2004
2	candesartanIBA 11/2008 - 03/2007
2	Plasminogen Activator Inhibitor 1IBA 05/2007 - 02/2002
2	Fibrinogen (Factor I)FDA Link 05/2007 - 02/2002
2	Immunoglobulin G (IgG)IBA 09/2006 - 11/2004
2	Plasminogen Activators (Plasminogen Activator)IBA 12/2003 - 02/2002
1	melanocortin 5 receptorIBA 01/2022
1	Puromycin AminonucleosideIBA 01/2022
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021
1	thiamine triphosphorate (TTP)IBA 01/2020
1	TristetraprolinIBA 01/2020
1	NPHS2 proteinIBA 01/2020
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Insulin (Novolin)FDA Link 01/2020
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2020
1	triptolideIBA 01/2020
1	Biological ProductsIBA 01/2020
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019
1	Long Noncoding RNAIBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 10/2018
1	CreatinineIBA 10/2018
1	InterleukinsIBA 10/2018
1	Macrophage Migration-Inhibitory FactorsIBA 10/2018
1	Interleukin-8 (Interleukin 8)IBA 10/2018

Therapy/Procedure

22	Therapeutics 11/2021 - 12/2011
3	Nephrectomy 01/2012 - 11/2004
2	Immunomodulation 10/2020 - 03/2014
2	Treatment Delay 11/2016 - 03/2014
1	Artificial Respiration (Mechanical Ventilation) 01/2021
1	Renal Dialysis (Hemodialysis) 01/2019
1	Renal Replacement Therapy (Therapies, Renal Replacement) 10/2018